PPS Silent® Surfactant

Use a Single-Tube, Zero Clean-Up Protocol to Extract, Solubilize, and Digest Proteins from Small Cell Populations.

Eliminate Buffer Changes and Sample Clean-Up Steps

Now you can use mass spectrometry to analyze proteins extracted from LCM samples and other small cell populations without pooling cells from multiple sections. PPS Silent Surfactant disrupts cell membranes, extracts and solubilizes proteins, then breaks down into non-surfactant hydrolytic cleavage products. The single-tube protocol prepares samples for nanoLC-MS/MS analysis without the use of salts or detergents which would necessitate yield-reducing sample clean-up prior to injection.

No Detergent Interference, No Oily Film, No Sticky Pellet

PPS Silent Surfactant is a cleavable surfactant capable of disrupting cell membranes and solubilizing proteins. At low pH, PPS hydrolyzes rapidly into cleavage products with no surfactant properties and no detergent interferences. And, unlike first-generation cleavable surfactants for mass spectrometry, there’s no oily film or sticky pellet to complicate sample preparation.

Our Offer

PPS Silent Surfactant comes in 10 mg and 1 mg vials packaged in popular vial-quantity configurations. A 5-pack of 1 mg vials is $199. Our quantity discount pricing for PPS is reflected on our price list. Please note that your purchase comes with our 30-day money-back guarantee. If youre dissatisfied with PPS Silent Surfactant for any reason, just send any unused materials back to us and well refund your money promptly.

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